Transgender women are around 49 times more likely to be living with HIV than other adults of reproductive age with an estimated worldwide HIV prevalence of 19%; in some countries the HIV prevalence rate in transgender women is 80 times that of the general adult population.
The lack of legal recognition of transgender in Uganda as a third gender has contributed to their exclusion and marginalization. Well as Transgender persons can change their names to match their preferred gender, they are required to undergo genital surgery before legal recognition of their gender. However, the constitution does not provide a procedure for change of sex for adults that transgender persons end up appearing.
According to a 2013 Pew Research Centre opinion survey, 96% of Ugandans declined any transgender (LGBT) activities and it is for that reason that Tranz Net Uganda (TNU) exists.